The Best TV Spin-Offs Ranked

4. Pinky and the Brain

Pinky and Brain had a recurring segment on Animaniacs back in 1993. They were such a popular duo, producers decided to give them their own series. Pinky and the Brain was born and lasted for 10 seasons.

The show followed genetically enhanced lab rats, as they lived in cages at Acme Labs. Each episode, Brain tried to come up with a plan to take over the world. Shockingly, it failed every time, but people kept on watching!

3. The Jeffersons

If you watched All in the Family, you may have been surprised that a show like The Jeffersons was a spin-off from it. Sherman Hemsley made it work from a small part in All in the Family into a successful sitcom of his own for 11 years.

The Jeffersons followed the lives of George and Louise Jefferson, as they were moving on up. Their on-set chemistry definitely had fans tuning in every week, but it also could have been their maid, Florence, too. Marla Gibbs was always good for some wisecracking joke and added just the right touch to this successful spin-off.

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2. Frasier

One of the most successful spin-offs to ever come about seemed like an odd pick when it first started. Dr. Frasier Crane was an extra on Cheers and just seemed like a character to fill a chair when he first started. The pompous psychiatrist soon turned into a character that fit perfectly into the bar, but his own show?

Yeah, it happened, as Dr. Crane relocated to Seattle and a hit was born! You can thank his pretentious brother Niles Crane (played by David Hyde Pierce, who earned 11 Emmy nominations for his role and won four of them) for making it a success. Add in his ex-cop father played by John Mahoney and the caregiver Daphne, played by Jane Leeves, and this was all a recipe for success. A success that spanned 11 seasons.

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